Seleucus I Nicator

• 358 BC
  Seleucus I Nicator, one of the Diadochi and the founder of the Seleucid Empire, is born in family of Philip II of Macedon's generals in Europos, the northern part of Macedonia
• May, 326 BC
  Macedonian army under Alexander the Great defeats Indian king Porus at the battle of The Hydaspes River in Punjab, modern-day Pakistan, expanding Alexandrian Empire to its maximum extent
• 324 BC, February
  Seleucus marries Apama, the Persian princess Apama, at the great marriage ceremony at Susa, arranged by Alexander of Macedon
• June 13, 323 BC
  Alexander the Great dies of fever after a feast in Babylon, which causes wars of the Diadochoi, his generals and friends, in the Empire
• 321 BC
  After assassination of Perdiccas, the regent of Alexander's empire, during The First War of the Diadochi, and partition of the empire between Perdiccas' opponents, Seleucus is appointed Satrap of Babylon under the new regent Antipater
• 312 BC
  Being forced to flee Babylon by Antigonus, Seleucus I Nicator returns to Babylon with the support of Ptolemy I Soter and formally establishes Seleucid Empire in Mesopotamia
• 305 BC
  Seleucus I Nicator, the Basileus of the Seleucid Empire, founds the city of Seleucia on the Tigris and makes it new capital of the empire, which eventually depopulates Babylon
• 305 BC
  Chandragupta Maurya, the first emperor of Mauryan Empire, seizes the satrapies of Paropanisadai, Aria, Arachosia and Gedrosia from Seleucus I Nicator, the Macedonian satrap of Babylonia, in return for 500 elephants
• 301 BC
  Antigonus I Monophthalmus, a Macedonian general and satrap under Alexander the Great, is defeated and killed by the united forces of Seleucus and Lysimachus at battle of Ipsus, ending the Fourth War of the Diadochi and confirming dissolution of Alexander's empire
• 281 BC
  Seleucus I Nicator invades Asia Minor and defeats Lysimachus, the King of Macedon and his last rival, in the Battle of Corupedium in Lydia, which leaves him the only living contemporary of Alexander the Great
• 281 BC
  Seleucus I Nicator, the founder of the Seleucid Empire, is assassinated by the King of Macedon Ptolemy Ceraunus, and is succeeded by his son Antiochus I as ruler of the Seleucid empire